Biotin anti-human Adiponectin (Acrp30) Antibody

Pricing & Availability
112-1 (See other available formats)
Regulatory Status
Other Names
GBP-28, apM1, AdipoQ, and Acrp30
Mouse IgG1, κ
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Product Citations
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528803 50 µg 141€
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528804 500 µg 465€
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Adiponectin, also referred as Acrp30, AdipoQ, apM1, and gelatin binding protein of 28 kD (GBP-28), is encoded by the ADIPOQ gene in humans. Adiponectin contains 244 amino acids with a collagen-like domain at the N-terminal and a globular domain at the C-terminal. The globular domain can be proteolytically truncated forming the globular adiponectin (gAdiponectin). This globular domain resembles the structure of the complement C1q and the TNF-α superfamily. Adiponectin exists in a wide range of homo-oligomers: a low-molecular weight (LMW) trimer, a medium molecular weight (MMW) hexamer, and a high molecular weight (HMW) multimer with little or no interconversion between the forms. Females generally have higher HMW than males in proportion and absolute amounts. Adiponectin has two receptors (adipoRs)-1 and -2. AdipoR1 mRNA is detectable in skeletal muscle, spleen, lung, heart, kidney, and liver. AdipoR2 is expressed in liver, but is also detectable in heart, lung, skeletal muscle, and kidney.

Adiponectin plays an important role in carbohydrate and lipid metabolism. It promotes insulin-sensitivity and protects cells from inflammation and apoptosis. It is also hypothesized to have anti-atherogenic activity. Normal circulating adiponectin level ranges from 4-30 µg/mL. Adiponectin levels are inversely correlated with body mass index (BMI). Low serum level of adiponectin is found in obesity, type 2 diabetes and those with coronary artery disease. Therefore, adiponectin serves as an important clinical biomarker for metabolic syndromes.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Recombinant human Adiponectin
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography and conjugated with biotin under optimal conditions.
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.

ELISA Detection - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 0.05-0.2 µg/ml is recommended. To obtain a linear standard curve, serial dilutions of Adiponectin protein ranging from 10,000 to 156 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

ELISA Detection: The biotinylated 112-1 antibody is useful as the detection antibody in a sandwich ELISA assay, when used in conjunction with the purified 62-9 antibody as the capture antibody and human Adiponectin protein as the standard.

For testing human Adiponectin (Acrp30) in serum, plasma, or supernatant, BioLegend’s ELISA LEGEND MAX™ Kits are specially developed and recommended.

AB_2571888 (BioLegend Cat. No. 528803)
AB_2571889 (BioLegend Cat. No. 528804)

Antigen Details

Protein hormone.
Adipose tissue.
Modulates a number of metabolic processes including glucose regulation and fatty acid oxidation.
Liver, heart, lung, skeletal muscle, and kidney.
Adiponectin receptor 2
Biology Area
Antigen References

1. Ouchi N, et al. 2000. Circulation 102:1296.
2. Ouchi N, et al. 1999. Circulation 100:2473-6.
3. Nakano Y, et al. 1996. J. Biochem. 120:803.
4. Yokota T, et al. 2000. Blood 96:1723.

Gene ID
9370 View all products for this Gene ID
View information about Adiponectin on

Related FAQs

How many biotin molecules are per antibody structure?
We don't routinely measure the number of biotins with our antibody products but the number of biotin molecules range from 3-6 molecules per antibody.
Go To Top Version: 3    Revision Date: 02.18.2016

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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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  • Biotin anti-human Adiponectin (Acrp30)


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