APC anti-mouse TCR Vγ2 Antibody

Pricing & Availability
UC3-10A6 (See other available formats)
Regulatory Status
Other Names
Vγ2 T-cell receptor, T cell receptor gamma 2
Armenian hamster IgG
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Product Citations
C57BL/6 mouse splenocytes were stained with CD3 PE and TCR Vγ2 (clone UC3-10A6) APC (top) or Armenian hamster IgG APC isotype control (bottom).
  • UC3-10A6_APC_1_072811
    C57BL/6 mouse splenocytes were stained with CD3 PE and TCR Vγ2 (clone UC3-10A6) APC (top) or Armenian hamster IgG APC isotype control (bottom).
  • UC3-10A6_APC_2_072811
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137707 25 µg 60,00€
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137708 100 µg 160,00€
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T cell receptor (TCR) Vγ2 bearing T lymphocytes make up a significant proportion of γδ TCR cells in late fetal and adult peripheral lymphoid tissues. TCR γδ T cells may play a role in immunological surveillance for stress-induced self-antigens. The frequency of Vγ2 expression in different strains varied from 12% to 54% in the TCR γδ repertoire. Variations in the levels of Vγ2+ cells are not associated with MHC haplotype. High Vγ2 expression is influenced by the TCR-δ locus.  Expanding Vγ2+ TCRγδ cells in B6 mice overwhelmingly use a Vδ7+ δ chain except in the DBA/2 strain. Clone UC3-10A6 reacts with the Vγ2 segment as designated by the Garman nomenclature1.

Product Details
Technical Data Sheet (pdf)

Product Details

Antibody Type
Host Species
Armenian Hamster
G8 mouse T cells
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.125 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Application References

(PubMed link indicates BioLegend citation)
  1. Dent AL, et al. 1990. Nature 343:714.
  2. Kelly KA, et al. 1993. Int. Immunol. 5:331.
  3. Sperling AI, et al. 1992. J. Immunol. 149:3200.
  4. Sperling AI, et al. 1997. J. Immunol. 159:86.
Product Citations
  1. Xiong S 2013. J Immunol. 190:3267. PubMed
  2. Shibata K, et al. 2014. J Immunol. 192:2210. PubMed
  3. Dong P, et al. 2014. PLoS One. 9:112964. PubMed
  4. Shevach H 2016. J Immunol. 196: 1517 - 1528. PubMed
  5. Marco Barros R, et al. 2016. Cell. 167: 203-218. PubMed
  6. Jandke A, et al. 2020. Nat Commun. 3.075694444. PubMed
  7. Fiala GJ, et al. 2019. J Immunol. 203:569. PubMed
AB_10899574 (BioLegend Cat. No. 137707)
AB_10897644 (BioLegend Cat. No. 137708)

Antigen Details

A member of Ig superfamily, associated with TCR δ chain and CD3 complex.

T cell subset in fetal and adult peripheral lymphoid tissues and thymus.

Might play a role in a previously unrecognized form of immunological surveillance for stress-induced self-antigens.
Cell Type
T cells
Biology Area
Adaptive Immunity, Immunology
Molecular Family
Antigen References

1. Allison JP, et al. 1991. Annu. Rev. Immunol. 9:679.
2. O’Brien RL, et al. 2000. J. Immunol. 165:6472.

Gene ID
110067 View all products for this Gene ID
View information about TCR Vgamma2 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 11.30.2012

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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