APC anti-mouse/human CD207 (Langerin) Antibody

Pricing & Availability
4C7 (See other available formats)
Regulatory Status
Other Names
Mouse IgG2a, κ
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Product Citations
Cells from a collagenase-digested BALB/c mouse spleen were stained with CD11c Alexa Fluor® 488 and CD207 (clone 4C7) APC (top) or mouse IgG2a, κ APC isotype control (bottom).
  • 4C7_APC_CD207_Antibody_FC_1_041013
    Cells from a collagenase-digested BALB/c mouse spleen were stained with CD11c Alexa Fluor® 488 and CD207 (clone 4C7) APC (top) or mouse IgG2a, κ APC isotype control (bottom).
  • 4C7_APC_CD207_Antibody_FC_2_041013
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144205 25 µg 102€
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144206 100 µg 260€
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CD207, also known as langerin, is a 40 kD single-pass type II transmembrane protein, member of the C-type lectin family. CD207 is expressed on the cell surface and Birbeck granules (BGs) of Langerhans cells, and subsets of thymic and splenic dendritic cells. Its ligands are mannose, n-acetylglucosamine, fucose, and sulfated glycans. Langerin is involved in the antigen processing pathway through capture and internalization of its ligands.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Mouse, Human
Reported Reactivity
Cynomolgus, Rabbit, Pig
Antibody Type
Host Species
Langerin extracellular domain-Fc fusion protein
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions.
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Red Laser (633 nm)
Product Citations
  1. Hartwig T et al. 2018. Cell reports. 25(13):3564-3572 . PubMed
  2. Samarchith P Kurup et al. 2019. Cell host & microbe. 25(4):565-577 . PubMed
  3. Wong E, et al. 2019. Cell Rep. 29:3047. PubMed
  4. Tran S, et al. 2020. Immunity. 53(3):627-640.e5. PubMed
AB_2561997 (BioLegend Cat. No. 144205)
AB_2561998 (BioLegend Cat. No. 144206)

Antigen Details

Single-pass type II transmembrane protein, 40 kD, one C-type lectin domain, homotrimer

Langerhans cells, subsets of thymic and splenic dendritic cells

Antigen uptake, antigen processing
Mannose, n-acetylglucosamine, fucose, sulfated glycans
Cell Type
Dendritic cells, Langerhans cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References

1. Romani N, et al. 2012. Curr. Top. Microbiol. Immunol. 351:113.
2. Kaplan DH. 2010. Trends Immunol. 31:446.
3. Clausen BE and Kel JM. 2010. Immunol. Cell. Biol. 88:351.
4. Merad M, et al. 2008. Nat. Rev. Immunol. 8:935.

Gene ID
246278 View all products for this Gene ID 50489 View all products for this Gene ID
View information about CD207 on UniProt.org

Related FAQs

There are no FAQs for this product.
Go To Top Version: 4    Revision Date: 12.08.2016

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering#license). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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