Alexa Fluor® 647 anti-mouse CD218a (IL-18Rα) Antibody

Pricing & Availability
A17071D (See other available formats)
Regulatory Status
Other Names
IL-1 Rrp, CDw218a, IL-18 receptor a
Rat IgG2b, κ
Ave. Rating
Submit a Review
Product Citations
C57BL/6 splenocytes were stained with CD3 PE and CD218a (IL-18Rα) (clone A17071D) (left) Alexa Fluor® 647 or rat IgG2b, κ (right) Alexa Fluor® 647 isotype control.
  • A17071D_A647_CD218a_Antibody_052720
    C57BL/6 splenocytes were stained with CD3 PE and CD218a (IL-18Rα) (clone A17071D) (left) Alexa Fluor® 647 or rat IgG2b, κ (right) Alexa Fluor® 647 isotype control.
Compare all formats See Alexa Fluor® 647 spectral data
Cat # Size Price Quantity Check Availability Save
157907 25 µg 115€
Check Availability

Need larger quantities of this item?
Request Bulk Quote
157908 100 µg 282€
Check Availability

Need larger quantities of this item?
Request Bulk Quote

The IL-18 receptor (IL-18R) complex is composed of two known chains, IL-18 receptor α (IL-18Rα) and IL-18 receptor β (IL-18Rβ). IL-18Rα (IL-1R5) is an IL-1 receptor super family member. It was originally described as IL-1 receptor-related protein (IL-1Rrp) because of its homology with the IL-1/Toll receptor family. IL-18Rα is the extracellular binding domain of the IL-18 receptor complex. It is expressed on the majority of peripheral CD4+ T cells, Th1 cells, and reciprocally repressed during Th2 development. The expression of IL-18Rα is induced by an IL-12/Stat4 pathway and inhibited by IL-4/Stat6 pathway. Binding of IL-18Rα together with IL-18β to proinflammatory cytokine IL-18 plays an important role in innate and autoimmune responses.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Antibody Type
Host Species
Recombinant mouse CD218a
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.
0.5 mg/mL
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.

FC - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633 nm / 635 nm.

Alexa Fluor® and Pacific Blue™ are trademarks of Life Technologies Corporation.

View full statement regarding label licenses
Excitation Laser
Red Laser (633 nm)
AB_2860736 (BioLegend Cat. No. 157907)
AB_2876539 (BioLegend Cat. No. 157908)

Antigen Details

An IL-1 receptor super family member

Expressed on T cells, NK cell subset, neutrophils, IL-12 stimulated tonsillar B cells, and intestinal epithelial cells (IEC).

Bind to pro inflammatory cytokine IL-18 and play an important role in innate and autoimmune responses.
Cell Type
B cells, Endothelial cells, Neutrophils, NK cells, T cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules, Cytokine/Chemokine Receptors
Antigen References
  1. Parnet P, et al. 1996. J. Biol. Chem. 271:3967. 
  2. Thomassen E, et al. 1998. J. Interferon Cytokine Res. 18:1077-88. 
  3. Debets R, et al. 2000. J. Immunol. 165:4950-6. 
  4. Smeltz RB, et al. 2001. J. Exp. Med. 194:143-53. 
Gene ID
16182 View all products for this Gene ID
View information about CD218a on

Related FAQs

There are no FAQs for this product.
Go To Top Version: 1    Revision Date: 05.27.2020

For research use only. Not for diagnostic use. Not for resale. BioLegend will not be held responsible for patent infringement or other violations that may occur with the use of our products.


*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.


BioLegend Inc., 8999 BioLegend Way, San Diego, CA 92121
Toll-Free Phone: 1-877-Bio-Legend (246-5343) Phone: (858) 768-5800 Fax: (877) 455-9587

This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-mouse CD218a (IL-18Rα)

  • APC anti-mouse CD218a (IL-18Rα)

  • PE anti-mouse CD218a (IL-18Rα)

  • Alexa Fluor® 647 anti-mouse CD218a (IL-18Rα)


Login / Register
Remember me
Forgot your password? Reset password?
Create an Account