IL-6 Pathway

IL-6 is a potent lymphoid cell growth factor that binds to IL-6Rα and gp130 receptors. IL-6 stimulates the growth and survival of certain B cells and T cells. IL-6 plays a role in host defense, acute phase reactions, immune response, and hematopoiesis. IL-6 is expressed by T cells, B cells, monocytes, fibroblasts, hepatocytes, endothelial cells, and keratinocytes.

 

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