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PE anti-rat CD335 (NKp46) Antibody

Pricing & Availability
Clone
WEN23 (See other available formats)
Regulatory Status
RUO
Other Names
NCR1, NKP46, LY94
Isotype
Mouse IgG1, κ
Ave. Rating
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Product Citations
publications
WEN23_PE_CD335_Antibody_032818
Rat splenocytes were stained with anti-rat CD335 PE (clone WEN23; left) or Mouse IgG1, κ Isotype control PE (right) followed by APC anti-rat CD161.
  • WEN23_PE_CD335_Antibody_032818
    Rat splenocytes were stained with anti-rat CD335 PE (clone WEN23; left) or Mouse IgG1, κ Isotype control PE (right) followed by APC anti-rat CD161.
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250803 25 µg £87
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250804 100 µg £226
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Description

CD335, also known as NKp46, is a glycoprotein of the natural cytotoxicity receptor (NCR) family with 2 Ig-like domains and a short cytoplasmic tail. CD335 expression is restricted to NK cells and a subset of NKT cells; it's not expressed in CD1d-restricted NKT cells. NKp46 functions as a cytotoxicity triggering receptor.

Product Details
Technical Data Sheet (pdf)

Product Details

Verified Reactivity
Rat
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Rat NKp46 ectodomain recombinant protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
Concentration
0.2 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application

FC - Quality tested
Recommended Usage

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Excitation Laser
Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
RRID
AB_2728232 (BioLegend Cat. No. 250803)
AB_2728233 (BioLegend Cat. No. 250804)

Antigen Details

Structure
Single-pass type I membrane protein, 46 kD; belongs to the natural cytotoxicity receptor (NCR) family; contains 2 Ig-like (immunoglobulin-like) domains.
Distribution

Mature and immature NK cells, subset of NKT cells, but not on CD1d-restricted NKT cells.

Function
NK cells activation
Ligand/Receptor
Viral hemagglutinins, heparan sulfate proteoglycans
Cell Type
NK cells, NKT cells
Biology Area
Immunology, Innate Immunity
Molecular Family
CD Molecules
Antigen References
  1. Westgaard IH, et al. 2004. J. Leuko. Biol. 76:1200.
  2. Falco M, et al. 1999. Immunol. Lett. 68:411.
  3. Caligiuri MA. 2008. Blood. 112:461.
Gene ID
117547 View all products for this Gene ID
UniProt
View information about CD335 on UniProt.org

Related FAQs

What type of PE do you use in your conjugates?
We use R-PE in our conjugates.
Go To Top Version: 0    Revision Date: 04/03/2018

For Research Use Only. Not for diagnostic or therapeutic use.

 

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This data display is provided for general comparisons between formats.
Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors.
If you need assistance with selecting the best format contact our expert technical support team.

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