Welcome to BioLegend’s one-of-a-kind advanced search. Search by any one of the single fields below or narrow down your searches by using multiple parameters. Looking for an anti-mouse NK cell antibody for IHC? Or looking for a FITC-conjugated antibody against a human marker for dendritic cells to use for flow cytometry? Only BioLegend’s advanced search can provide you with the best answers. If you have further questions, please contact our technical service team at 858-768-5801.
Use this document lookup tool to find Current Product Datasheets, Certificates of Analysis, or MSDS for any antibody products you have purchased from BioLegend.
Use the search box below to perform a site search of BioLegend.com powered by Google™.
Recombinant Human Paxillin
Recombinant Human Paxillin
565501
25 µg
¥56,000
Product Details
Source:
E. coli, approximately 88 kD (Full-length human paxillin protein with Trx-tag, His-tag, and S-tag sequences).
Formulation:
This protein is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Storage & Handling:
Contains no protein stabilizer. Store at ≤ -20°C in a non-defrosting freezer and minimize repeated freeze/thaw cycles.
10ng of Paxillin recombinant protein was resolved by electrophoresis, transferred to nitrocellulose, and probed with anti-Paxillin antibody (Clone PAX227). Proteins were visualized using a goat anti-mouse secondary conjugated to HRP and chemiluminescence detection.
Description:
Recombinant full-length human paxillin produced in E. coli with >70% purity as determined by Comassie Blue staining of an SDS-PAGE gel. Paxillin (also known as peroxisomal membrane protein 3) is a cytoplasmic protein with LIM metal-binding repeat homology and LIM domains. Endogenous paxillin has three isoforms designated as α, β, γ; with approximate molecular weights of 68 kD. Paxillin is localized to actin-membrane attachment at sites of cell adhesion to extracellular matrix (focal adhesion). This protein undergoes cell adhesion-dependent tyrosine phosphorylation. Paxillin has been shown to interact with FAK, vinculin, src, Crk, p210BRC / ABL, talin, and integrin-β1.
1. Leventhal P, et al. 1997. J. Biol. Chem. 272:5214. 2. Mazaki Y, et al. 1997. J. Biol. Chem. 272:7437. 3. Kirchner J, et al. 2003. J. Cell Sci. 116:975. 4. Tang D, et al. 2003. J. Physiol. 553:21.
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
