Antibodies
Login
Search   
Purified anti-RIG-1 Antibody
Purified anti-RIG-1 Antibody
635201 25 µg $95.00     
635202 100 µg $195.00     
Product Details
Clone: SS1A
Isotype: Rat IgG2a, κ
Reactivity: Mouse
Immunogen: Peptide-KLH, C-terminal end of murine RIG-1
Formulation:

This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide at 0.5 mg/ml.
Preparation: This antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: Upon receipt, store undiluted at 4°C.
Application:

WB - Quality tested
Recommended Usage:

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 1 µg per ml. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
Enter Lot#:   
 Western blot analysis of extracts
Western blot analysis of extracts from NIH3T3 cells (Lane 1) and mouse splenocytes (Lane 2), using anti-RIG1, SS1A.


Compare all formats



Description:

RIG-1/DDX58(Retinoic acid-inducible gene 1 protein/ DEAD-box protein 58) is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARD domains, a helicase ATP-binding domain and a helicase C-terminal domain. Predicted molecular weight approximately 107 kD. RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses. RIG-1 and MDA5 (melanoma differentiation-associated gene 5) are key intracellular receptors that sense intracellular viral infection and trigger a signal forinnate antiviral responses including the production of typeI IFN. Clone SS1A has been shown to be useful for western blotting of the mouse RIG-1 protein.
Other Names: Retinoic acid-inducible gene 1 protein, DEAD-box protein 58, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 M
Structure: RIG-1 is an RNA helicase that belongs to the DEAD/H box. Contains 2 CARD domains, a helicase ATP-binding domain and a helicase C-terminal domain. Predicted molecular weight approximately 107 kD.
Distribution: Cytoplasm.
Function: Involved in innate immune defense against viruses. RIG-1 has an essential function in double-stranded RNA-induced innate antiviral responses. RIG-1 is one of the key intracellular receptors that sense intracellular viral infection and trigger a signal for
Interaction: Cardif
Antigen
References:

1. Imaizumi T, et al. 2002. Biochem. Biophys. Res. Commun. 292:274
2. Kato H, et al. 2006. Nature 441:101
3. Kato H, et al. 2005. Immunity 23:19
GeneID: 109906
Latest Publications: View the latest RIG-1 articles on HighwirePress.com
UniProt: View information about RIG-1 on UniProt.org
Keywords: Purified anti-RIG-1, SS1A, Purified, Retinoic acid-inducible gene 1 protein, DEAD-box protein 58, DEAD (Asp-Glu-Ala-Asp) box polypeptide 58 M , Mouse, Immunology, Antibodies
Related Products
DescriptionCloneApplications
AKP Goat anti-rat IgG (minimal x-reactivity)Poly4054ELISA, WB
HRP Goat anti-rat IgG (minimal x-reactivity)Poly4054ELISA, WB, IHC
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
x
Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
  • Purified anti-RIG-1
    Western blot analysis of extracts

    Western blot analysis of extracts from NIH3T3 cells (Lane 1) and mouse splenocytes (Lane 2), using anti-RIG1, SS1A.

x
Copyright © 2011 BioLegend, Inc. All rights reserved.