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Purified anti-mouse CD83 Antibody
Purified anti-mouse CD83 Antibody
121502 100 µg $175.00     

Product Details

 
Clone: Michel-19 (See other available formats)
Isotype: Rat IgG1, κ
Isotype Control:Purified Rat IgG1, κ Isotype Ctrl
Reactivity: Mouse
Immunogen: Recombinant mouse CD83 protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted at 4°C.
Application:

FC - Quality tested

Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

COA:
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Application
Notes:

Additional reported applications (for relevant formats of this clone) include: immunohistochemistry of acetone - fixed frozen sections4.

Application
References:

  Publication Library
Purified anti-mouse CD83 Antibody Michel-19 Image 1
mCD83 transfected cells stained with purified Michel-19, followed by anti-rat IgG FITC


Compare all formats



Description:

CD83 is a 45 kD type I transmembrane protein. It belongs to immunoglobulin superfamily and is expressed on mature dendritic cells and activated lymphocytes. CD83 is involved in the regulation of T cell development and immune response. Soluble form CD83 has been reported to inhibit dendritic cell maturation and dendritic cell-mediated T cell proliferation. Murine CD83 ligand has been found on B cells.

Other Names: HB15
Structure: Type I transmembrane protein, Ig superfamily, 45kD
Distribution: Mature dendritic cells, activated lymphocytes
Function: Regulate T cell development and immune response, soluble form CD83 inhibit dendritic cell maturation
Ligand Receptor: CD83 ligand
Antigen
References:

1. Lechmann M, et al. 2005. Biochem. Biophys. Res. Commun. 329:132.
2. Kotxor N, et al. 2004. Immunobiology 209:129.
3. Leon F, et al. 2004. J. Immunol. 173:2995.
4. Cramer SO, et al. 2000. Int. Immunol. 12:1347.
5. Fujimoto Y, et al. 2002. Cell 108:755.

GeneID: 12522
Latest Publications: View the latest CD83 articles on HighwirePress.com
UniProt: View information about CD83 on UniProt.org
Keywords: Purified anti-mouse CD83, Michel-19, Purified, HB15, Mouse, Flow Cytometry, Immunology, Antibodies
Related Products

DescriptionCloneApplications
APC Goat anti-rat IgG (minimal x-reactivity)Poly4054FC
FITC Goat anti-rat IgG (minimal x-reactivity)Poly4054FC
PE Goat anti-rat IgG (minimal x-reactivity)Poly4054FC
Cell Staining BufferFC, ICC, ICFC
Purified Rat IgG1, κ Isotype CtrlRTK2071FC, ICFC, ICC, IF, IHC, IP, WB


Other Formats

DescriptionCloneApplications
Alexa Fluor® 488 anti-mouse CD83Michel-19FC
Alexa Fluor® 647 anti-mouse CD83Michel-19FC
APC anti-mouse CD83Michel-19FC
Biotin anti-mouse CD83Michel-19FC
Brilliant Violet 650™ anti-mouse CD83Michel-19FC
FITC anti-mouse CD83Michel-19FC
PE anti-mouse CD83Michel-19FC

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

Version: 1 Revision Date: 2012-11-30
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Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-mouse CD83
    mCD83 transfected cells stained with

    mCD83 transfected cells stained with purified Michel-19, followed by anti-rat IgG FITC

  • Biotin anti-mouse CD83
    mCD83 transfected cells stained with

    mCD83 transfected cells stained with biotinylated Michel-19, followed by Sav-PE

  • FITC anti-mouse CD83
    mCD83 transfected cells stained with

    mCD83 transfected cells stained with Michel-19 FITC

  • PE anti-mouse CD83
    mCD83 transfected cells stained with

    mCD83 transfected cells stained with Michel-19 PE

  • APC anti-mouse CD83
    mCD83 transfected cells stained with

    mCD83 transfected cells stained with Michel-19 APC

  • Alexa Fluor® 488 anti-mouse CD83
    mCD83 transfected cells stained with

    mCD83 transfected cells stained with Michel-19 Alexa Fluor® 488

  • Alexa Fluor® 647 anti-mouse CD83
    mCD83 transfected cells stained with

    mCD83 transfected cells stained with Michel-19 Alexa Fluor® 647

  • Brilliant Violet 650™ anti-mouse CD83
    Mouse CD83 transfected cells stained

    Mouse CD83 transfected cells stained with Michel-19 Brilliant Violet 650™.

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