Welcome to BioLegend’s one-of-a-kind advanced search. Search by any one of the single fields below or narrow down your searches by using multiple parameters. Looking for an anti-mouse NK cell antibody for IHC? Or looking for a FITC-conjugated antibody against a human marker for dendritic cells to use for flow cytometry? Only BioLegend’s advanced search can provide you with the best answers. If you have further questions, please contact our technical service team at 858-768-5801.
Catalog Number
Specificity
GeneID
Clone
Format
Species Reactivity
Applications
Cell Type
Keywords
*To perform a multi-parameter search, be sure to click on "Match all fields" below:
Match all fields
Match any field
Exact match
Partial match
Use this document lookup tool to find Current Product Datasheets, Certificates of Analysis, or MSDS for any antibody products you have purchased from BioLegend.
Use the search box below to perform a site search of BioLegend.com powered by Google™.
Each lot of this antibody is quality control tested by Western blotting. For Western blotting, suggested working dilution(s): Use 5-10 μg per 5 ml antibody dilution buffer for each mini-gel. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
Enter Lot#:
Application References:
1. Murray G, et al. 1998. Gut. 43:791. (IHC) 2. Murray G, et al. 1998. J. Pathol. 185:256. (IHC) 3. Duncan ME, et. al. 1998. Eur. J. Biochem. 258:37. (IHC)
Purified human MMP-9 (500 ng per lane) was resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody against MMP-9, clone F11P2C3.
Matrix metalloproteinases (MMPs) are zinc-dependent endopeptidases that degrade substances within the extracellular matrix. The MMP family includes six different groups of enzymes: collagenases, gelatinases, stromelysins, transmembrane MMPs, matrilysins and others. MMPs are secreted as proenzymes that have to be cleaved in order to be activated. Other MMPs, plasmins as well as other factors activate MMPs. MMPs are thought to play an important role in tissue remodeling associated with various physiological and pathological processes. MMP9 degrades of proteins in the extracellular matrix and activates growth factors like proTGFb and proTNFa. MMP-9 contributes to the invasion and metastasis of various human malignancies. Clone F11P2C3 has been shown to be useful for western blotting and immunohistochemistry of human MMP9.
Other Names:
Gelatinase B; CLG4B; Collagenase type IV, 92 KD; Gelatinase, 92 KD; Collagenase type V, MMP-9
Structure:
Belongs to the peptidase M10A family. Contains 3 fibronectin type-II domains and 4 hemopexin-like domains. Predicted molecular weight approximately 78 kD.
Interaction:
MMP2, MMP9, Fibronectin 1, Nidogen 1, Integrin a5, Integrin a2, Matrilin 2, Bone morphogenic protein 1, PDGFb, FGF7, CD44, CD36, Collagen, type VII, alpha 1
Bioactivity/Activities:
MMP9 degrades of proteins in the extracellular matrix and activates growth factors like proTGFb and proTNFa. MMP-9 contributes to the invasion and metastasis of various human malignancies.
Antigen References:
1. Huhtala P, et al. 1991. J. Biol. Chem. 266:16485.
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
Purified anti-MMP9
Purified human MMP-9 (500 ng per lane) was resolved by electrophoresis, transferred to nitrocellulose, and probed with monoclonal antibody against MMP-9, clone F11P2C3.