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Purified anti-human STRO-1 Antibody
Purified anti-human STRO-1 Antibody
340101 25 µg ¥22,000     
340102 100 µg ¥55,000     

Product Details

Clone: STRO-1
Isotype: Mouse IgM, λ
Isotype Control:Purified Mouse IgM, λ Isotype Ctrl
Reactivity: Human
Immunogen: Human CD34+ bone marrow cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted at 4°C.
Application:

FC - Quality tested

Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

COA:
Enter Lot#:   
Application
References:

1. Simmons PJ and Torok-Storb B. 1991. Blood 78:55.




Description:

STRO-1 is a cell surface antigen recognized by mAb STRO-1. It is expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors. In combination with glycophorin A (GPA), STRO-1 is a useful marker for identification of mesenchymal stem cells. It has been reported that STRO-1+/GPA- bone marrow cell subset can be used as a universal stromal feeder layer for hematopoietic stem/progenitor cells. This subset of cells has multipotent to differentiate into fibroblasts, adipocytes, osteoblasts, chondrocytes, and vascular smooth muscle-like cells.

Distribution: Mesenchymal stromal cells, nucleated erythroid precursors
Antigen
References:

1. Simmons PJ and Torok-Storb B. 1991. Blood 78:55.
2.Stewart K, et al. 1999. Bone Miner Res. 14:1345.
3. 3. Dennis JE, et al. 2002. Cell Tissues Organs. 170:73.
4.Goncalves R,et al. 2006. Exp. Hematol. 34:1353.

GeneID: NA
Latest Publications: View the latest STRO-1 articles on HighwirePress.com
UniProt: View information about STRO-1 on UniProt.org
Keywords: Purified anti-human STRO-1, STRO-1, Purified, Human, Immunology, Antibodies
Related Products

DescriptionCloneApplications
Purified Mouse IgM, λ Isotype CtrlMOPC-104EFC, ICC, IF, IHC, IP, WB

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