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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
Human prostatic adenocarcinoma cell line LNCaP stained with purified LNI-17 conjugated to PE
PSMA (prostate-specific membrane antigen) is a type II transmembrane zinc metallopeptidase, belonging to the M28 peptidase family. It possesses hydrolyzing enzyme activities and is also known as FOLH1 (folate hydrolase 1), GCP2 (glutamate carboxypeptidase II), NAALADase I (N-acetylated-alpha-linked acidic dipeptidase I). PSMA is expressed by normal and malignant prostate epithelial cells, by urothelial adenocarcinoma, and vasculatures of other malignancies. It is also found in the nervous system.
Type II transmembrane zinc metallopeptidase, M28 peptidase family
Distribution:
Epithelial cells in prostate, intestine and kidney tissue, nervous system
Function:
Hydrolyzing enzyme activity
Antigen References:
1. Silver DA, et al. 1997. Clin. Cancer Res. 3:81. 2. Troyer JK, et al. 1995. Int. J. Cancer. 62:552. 3. Mannweiler S, et al. 2009. Pathol. Oncol. Res. 15:167.
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This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
Purified anti-human PSMA (FOLH1)
Human prostatic adenocarcinoma cell line LNCaP stained with purified LNI-17 conjugated to PE
PE anti-human PSMA (FOLH1)
Human prostatic adenocarcinoma cell line LNCaP stained with LNI-17 PE
Alexa Fluor® 488 anti-human PSMA (FOLH1)
Human prostatic adenocarcinoma cell line LNCaP stained with LNI-17 Alexa Fluor® 488
APC anti-human PSMA (FOLH1)
Human prostatic adenocarcinoma cell line LNCaP cells were stained with PSMA (clone LNI-17) APC (filled histogram) or mouse IgG1 APC isotype control (open histogram).
