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Purified anti-human Factor H Antibody
Cat. # Size Price  

518401 50 µg $85.00
518402 500 µg $275.00
Product Details

Clone: C18/3 (See other available formats)
Isotype: Mouse IgG1, κ
Reactivity: Human
Immunogen: Human Complement Factor H
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: ELISA Capture - Quality tested
WB - Reported in the literature
Recommended Usage: Each lot of this antibody is quality control tested by ELISA assay. For ELISA capture applications, a concentration range of 2-8 µg/ml is recommended. To obtain a linear standard curve, serial dilutions of Factor H recombinant protein ranging from 78 to 5000 pg/ml are recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.
ELISA Capture: The purified C18/3 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated L20/3 antibody (Cat. No. 518504) as the detection antibody.

(PubMed link indicates BioLegend citation)
  Publication Library
RRID: AB_10933257 (BioLegend Cat. No. 518401)
AB_10895906 (BioLegend Cat. No. 518402)
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Antigen Details

Description: Factor H, a 155 kD soluble glycoprotein, is a member of the regulators of complement activation family and is a complement control protein. It circulates in human plasma at a concentration of 500–800 mg/ml that provides critical negative regulation to the alternative pathway of complement cascade. Factor H is secreted by Kupffer cells, hepatocytes, vascular endothelial cells, and platelets. Overactive factor H may result in reduced complement activity on pathogenic cells, increasing susceptibility to microbial infections. Underactive factor H may result in increased complement activity on healthy host cells, resulting in autoimmune diseases.
Other Names: Complement Factor H
1. Ripoche J, et al. 1988. Biochem. J. 249:593.
2. Rodríguez de Córdoba S, et al. 2004. Mol. Immunol. 41:355.
GeneID: 3075
UniProt: View information about Factor H on
Keywords: Purified anti-human Factor H, C18/3, Purified, Complement Factor H , Human, ELISA Capture, Western Blotting, Immunology, Antibodies
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Related Protocols

Sandwich ELISA Protocol

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Related Pages

Quality Control
Cytokines/Chemokines Mobile Application
Interleukin Receptors
Chemokines and Chemokine Receptors
ELISA Kits and Sets

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

Version: 1 Revision Date: 2012-11-30
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This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-human Factor H

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