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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
Human peripheral blood lymphocytes stained with purified ASL-24 conjugated with PE.
CD82 is a 45-90 kD type III tetraspan membrane protein which is encoded by the KAI1 gene. A member of the 4-span transmembrane protein superfamily (TM4SF) CD82 forms a complex with CD37, CD53, CD81, ECM and MHC molecules. CD82 is expressed on monocytes, granulocytes, lymphocytes, epithelial cells, endothelial cells, and fibroblasts and plays a role in signal transduction and adhesion. It has been suggested CD82 functions as a tumor suppressor as loss of expression has been found to promote tumor metastasis.
Other Names:
KAI1, C33, R2, 4F9, IA4
Structure:
Type III tetraspan membrane protein, 45-90 kD, complexed with CD37, CD53, CD81, ECM and MHC molecules, 4-span transmembrane protein superfamily (TM4SF)
Signal transduction, adhesion, tumor metastasis suppressor
Ligand Receptor:
KITENIN
Antigen References:
1. Miranti CK. 2009. Cell. Signal. 21:196 2. Abe M, et al. 2008. 266:163 3. Lee JH et al. 2004. Cancer Res. 64:4235 4. Lagaudriere-Gesbert C, et al. 1997. J. Immunol. 158:2790
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
Purified anti-human CD82
Human peripheral blood lymphocytes stained with purified ASL-24 conjugated with PE.
PE anti-human CD82
Human peripheral blood lymphocytes stained with ASL-24 PE.
Alexa Fluor® 488 anti-human CD82
Human peripheral blood lymphocytes stained with ASL-24 Alexa Fluor® 488
Alexa Fluor® 647 anti-human CD82
Human peripheral blood lymphocytes stained with ASL-24 Alexa Fluor® 647
