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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
Human peripheral blood lymphocytes stained with Purified LNH-94 conjugated with PE
CD298 or the β3 Na+/K+ ATPase, is a 42 kD type II transmembrane protein, also known as ATP1B3. An integral plasma membrane protein, Na+/K+ ATPase is composed of one α and one β subunits. Four isoforms of the α and three isoforms of the β subunits have been reported. Na+/K+ ATPase couples ATP hydrolysis to the development of an ionic gradient by pumping Na+ and K+ ions in opposite directions across the cell plasma membrane. It has broad tissue distribution, including all leukocytes and many other tissues.
Other Names:
Na+/K+ ATPase β3, ATP1B3
Structure:
CD298 is the β3 subunit of Na+/K+ ATPase, type II transmembrane protein
Distribution:
Broad expression including all leukocytes and other tissues
Function:
sodium-potassium pump, moves these Na+ and K+ ions in opposite directions across cell plasma membrane
Antigen References:
1. Zola H, et al. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers Wiley-Liss A John Wiley & Sons Inc, Publication 2. Chiampanichayakul S, et al. 2006. Tissue Antigens. 68:509 3. Malik N, et al. 1996. J. Biol. Chem. 271:22754
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This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
Purified anti-human CD298
Human peripheral blood lymphocytes stained with Purified LNH-94 conjugated with PE
PE anti-human CD298
Human peripheral blood lymphocytes stained with LNH-94 PE
