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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
Application References:
1. Wood GS, et al. 1983. J. Immunol. 131:212.
Human T lymphoblastic leukemia cell line Molt-4 stained with SK9 PE
CD1a is a 49 kD member of the immunoglobulin superfamily also known as T6 and R4. It is a type I membrane glycoprotein with structural similarities to MHC class I and is non-covalently associated with β2-microglobulin. CD1a plays a role in non-peptide glycolipid antigen presentation to CD1-restricted T cells. It is expressed on cortical double positive and single positive thymocytes, Langerhans cells, and dendritic cells. In addition to antigen presentation, CD1a has been implicated in thymic T cell development.
Other Names:
T6, R4, Leu-6
Structure:
Ig superfamily, MHC I-like molecule, type I transmembrane glycoprotein, 49 kD
Antigen presentation, lymphocyte activation, thymic T cell development
Ligand Receptor:
CD1-restricted TCRs
Antigen References:
1. Wood GS, et al. 1983. J. Immunol. 131:212. 2. Wood GS, et al. 1985. Am. J. Pathol. 120:371. 3. Martin LH, et al. 1987. P. Natl. Acad. Sci. USA 84:9189.
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This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
Purified anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with SK9 PE
PE anti-human CD1a
Human T lymphoblastic leukemia cell line Molt-4 stained with SK9 PE
Biotin anti-human CD1a
Human T lymphoblastic cell line, MOLT-4, stained with biotinylated SK9, followed by Sav-PE
