Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤2.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Additional reported applications include: block binding of PVR ligands CD226 and CD96 to PVR, immunoprecipitation, and western blot.
CD155, known as poliovirus receptor (PVR) or nectin-like 5, is a 70 kD type I transmembrane glycoprotein. It is a nectin-like molecule belonging to Ig superfamily. CD155 is primarily found on endothelial cells, monocytes, epithelia and central nervous system. CD155 is an adhesion molecule involved in cell-cell and cell-matrix adhesion through interaction with CD226, CD96 (Tactile), nectin-1, -2, and -3 (CD111, CD112, CD113), and vitronectin. It also serves as a receptor for poliovirus and cytomegalovirus.
Poliovirus receptor (PVR), nectin-like 5
Type I glycoprotein, Ig superfamily
Monocytes, endothelial cells, epithelia, central nervous system
Cell-cell and cell-matrix adhesion
CD226, CD96, nectin-1, -2, and -3, vitronectin, CD155, poliovirus
1. Zola H, et al. eds. 2007. Leukocyte and Stromal Cell Molecules:The CD Markers. Wiely-Liss A John Wiley & Sons Inc, Publication 2. Bottino PD, et al. 2005. Mol. Immunol. 42:463 3. Tahara-Hanaoka S, et al. 2004. Intl. Immunol. 16:533
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This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
PE anti-human CD155 (PVR)
Human histiocytic lymphoma cells U-937 stained with SKII.4 PE
Purified anti-human CD155 (PVR)
Human histiocytic lymphoma cells U-937 stained with purified SKII.4, followed by anti-mouse IgG FITC
PerCP/Cy5.5 anti-human CD155 (PVR)
U937 cells were stained with CD155 (clone SKII.4) PerCp/Cy5.5 (filled histogram) or mouse IgG1, κ PerCp/Cy5.5 isotype control (open histogram).
PE/Cy7 anti-human CD155 (PVR)
U937 cells were stained with CD155 (clone SKII.4) PE/Cy7 (filled histogram) or mouse IgG1, κ PE/Cy7 isotype control (open histogram).
PE/Dazzle™ 594 anti-human CD155 (PVR)
U937 cells were stained with CD155 (clone SKII.4) PE/Dazzle™ 594 (filled histogram) or mouse IgG1, κ PE/Dazzle™ 594 isotype control (open histogram).
APC anti-human CD155 (PVR)
U937 cells were stained with CD155 (clone SKII.4) APC (filled histogram) or mouse IgG1, κ APC isotype control (open histogram).