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Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤ 2.0 µg per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
Application Notes:
Additional reported applications: immunoprecipitation(1), blocking the interaction between ICAM-2 and LFA-1(1), immunohistochemical staining(2) of frozen tissue sections
Application References:
1. DeFougerolles AR,et al.1991.J. Exp.Med.174:253. 2. Van Herpen CML,et al.2005.Clin. Cancer Res.11:1899
Human peripheral blood lymphocytes stained with purified CBRIC2/2, followed by anti-mouse IgG FITC
CD102 is a 55 kD type I transmembrane glycoprotein, belongs to immunoglobulin superfamily, also known as Intercellular Adhesion Molecule-2, or ICAM-2. CD102 is constitutively expressed on vascular endothelial cells, some lymphocytes, monocytes, and platelets. CD102 is thought to be involved in lymphocyte recirculation and in costimulation of immune response. CD102 is a counter receptor of LFA-1 (CD11a/CD18), DC-SIGN and MAC-1.
Other Names:
Intercellular Adhesion Molecule-2, ICAM-2
Structure:
55 kD type I transmembrane glycoprotein, Ig superfamily
1.Weber KSC, et al.2004.Inflammation.28:177. 2.Barclay A, et al.1997 The Leukoycte Antigen FactsbookAcademic Press. 3. Casasnovas JM, et al.1999.P. Natl. Acad. Sci. USA96:3017. 4. Diamonds MS, et al.1990. J. Cell Biol.111:3129.
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This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
Purified anti-human CD102 (ICAM-2)
Human peripheral blood lymphocytes stained with purified CBRIC2/2, followed by anti-mouse IgG FITC
PE anti-human CD102 (ICAM-2)
Human peripheral blood lymphocytes stained with CBR-IC2/2 PE
FITC anti-human CD102 (ICAM-2)
Human peripheral blood lymphocytes stained with CBRIC2/2 FITC
