VEGF IL-6 IL-10 IL-10 IL-10 IL-10 IL-10 IL-10 IL-10 IL-6 IL-6 IL-6 TGF-B IFN-y IL-12 CD86 CD80 VEGF VEGF VEGF VEGF FGF STAT3 STAT3 stat3 STAT3 STAT3 STAT3 Tregs FOXP3 STAT3 STAT3 Cell Markers MHC Class I Cell Markers Cell Markers FOXP3 CD8 CD8 Cell MArkers STAT3 STAT3 STAT3 STAT3 STAT3 STAT3 STAT3 STAT3 Stat3-mediated Tumor Escape