CD8 CD127 CXCR5 ICOSL TGF-B IL-4 Bcl-6 Cell Markers Cell Markers IgM IgE IgG1 IgG2 IgG3 IgG2b IgA CD8 CD8 CTLA-4 FOXP3 CD4 CD8 TCR ICOSL STAT3 IL-6R OX-40 CD40L TCR CD28 ICOS IL-6 IL-6 ICOSL ICOSL MHC Class II OX-40L B7 CD40 ICOSL IL-21R BCR MHC Class II IL-21 IL-21 IL-27 CD84 IL-21 IL-2 IL-15 CXCR5 CXCR5 CXCR5 CXCR5 CXCR5 CD28 CXCR5 CXCR5 CCR4 CXCR5 CXCR5 Cell Markers Cell Markers Cell Markers Cell Markers Cell Markers SLAM SLAM CD8 GITR Cell Markers Cell Markers Cell Markers Cell Markers Cell Markers Cell Markers Cell Markers Cell Markers TNF IFN-y CXCR5 CXCR3 T-bet IL-12 IL-4 IL-13 CCR3 CCR4 IL-4 ICOSL ICOS CD69 CXCR5 TGF-B TGF-B TGF-B CD4 CD3 CD28 CCR7 TCR B7-1 B7-2 MHC Class II IL-6 IL-23 IL-22 IL-17 CCR6 STAT3 ROR-a ROR-a Cell Markers FOXP3 IL-21 BCL IL-10 IL-21R CD28 CTLA-4 IL-6 IL-1 IL-10 IL-1Ra TNF-a BCL-6 SAP Perforin CD29 CD49d CD25 CD44 CD122 CXCL13 CXCL13 CXCL13 CXCL13 CXCL13 GATA3 T Follicular Helper Cell Pathway