CREB RSK p53 NF-kB NF-kB PAX PAX CHOP c-Myc c-Jun c-Fos p38 p38 STAT JNK1 JNK1 ERK2 ERK2 PKA PKA PKC PKC SRC TNF TNFR IL-1 p130 b-Raf Integrin a/b BCL-2 HSF CREB IL-1R MAPK Signaling