NF-kB STAT3 STAT3 STAT3 STAT3 STAT3 STAT3 STAT3 STAT3 NF-kB SOCS mTOR Akt Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine Phosphotyrosine ERK2 ERK2 ERK2 ERK2 ERK2 IL-6R IL-6 IkB Raf c-Myc Timp1 SOCS IL-6 Pathway