Welcome to BioLegend’s one-of-a-kind advanced search. Search by any one of the single fields below or narrow down your searches by using multiple parameters. Looking for an anti-mouse NK cell antibody for IHC? Or looking for a FITC-conjugated antibody against a human marker for dendritic cells to use for flow cytometry? Only BioLegend’s advanced search can provide you with the best answers. If you have further questions, please contact our technical service team at 858-768-5801.
Use this document lookup tool to find Current Product Datasheets, Certificates of Analysis, or MSDS for any antibody products you have purchased from BioLegend.
Use the search box below to perform a site search of BioLegend.com powered by Google™.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 µl to 5 µl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 µl staining volume or per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.
COA:
Application Notes:
Additional reported applications (for the relevant formats) include: blocking of T cell activation, and partical blocking of B cell costimulation2. The LEAF™ purified antibody (Endotoxin <0.1 EU/μg, Azide-Free, 0.2 μm sterile-filtered) is recommended for functional assays (Cat. No. 309212).
Cy3, Cy5, Cy5.5 and Cy7 are subject to proprietary rights of GE Healthcare Bio-Sciences Corp. and Carnegie Mellon University and made and sold under license from GE Healthcare Bio-Sciences Corp. Sale of this product is licensed for research use only.
Application References:
1. Schlossman S, et al. Eds.1995. Leucocyte Typing V Oxford University Press. New York. 2. Hughes CCW, et al. 1996. J. Biol. Chem. 271:5369.
Human peripheral blood lymphocytes stained with TS1/8 PE/Cy7
CD2 is a 50 kD type I transmembrane glycoprotein also known as LFA-2, T11, and sheep red blood cell receptor (SRBC-R). This immunoglobulin superfamily member is expressed on thymocytes, T lymphocytes, NK cells, and thymic B cell subsets. The major ligand for CD2 is CD58 (also known as LFA-3). CD2 has also been reported to bind CD48, CD59, and CD15. CD2 plays a critical role in alternative T cell activation, T cell signaling, and cell-cell adhesion.
Other Names:
LFA-2, T11, SRBC-R
Structure:
Ig superfamily, type I transmembrane glycoprotein, 50 kD
Distribution:
T cells, NK cells, thymocytes, and thymic B cell subsets
Function:
T cell activation, adhesion
Ligand Receptor:
CD58 (LFA-3), CD48, CD59, CD15
Antigen References:
1. Bell G, et al. 1995. J. Immunol. 155:2805. 2. Bierer B, et al. 1989. Annu. Rev. Immunol. 7:579. 3. Moingeon P, et al. 1989. Immunol. Rev. 111:111.
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
Biotin anti-human CD2
Human peripheral blood lymphocytes stained with biotinylated TS1/8 and detected with Sav-PE
FITC anti-human CD2
Human peripheral blood lymphocytes stained with TS1/8 FITC
LEAF™ Purified anti-human CD2
Human peripheral blood lymphocytes stained with LEAFTM purified TS1/8 and detected with anti-mouse IgGs FITC
PE anti-human CD2
Whole blood lymphocytes stained
with TS1/8 PE
PE/Cy5 anti-human CD2
Human peripheral blood lymphocytes stained with TS1/8 PE/Cy5
Purified anti-human CD2
Human peripheral blood lymphocytes stained with purified TS1/8 and detected with anti-mouse IgGs FITC
Pacific Blue™ anti-human CD2
Human peripheral blood lymphocytes stained with TS1/8 Pacific Blue™
PE/Cy7 anti-human CD2
Human peripheral blood lymphocytes stained with TS1/8 PE/Cy7
Brilliant Violet 421™ anti-human CD2
Human peripheral blood lymphocytes stained with (clone TS1/8) Brilliant Violet 421™ (filled histogram) or mouse IgG1 Brilliant Violet 421™ isotype control (open histogram).
