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PE anti-mouse DLL1 Antibody
PE anti-mouse DLL1 Antibody
128307 50 µg £96     
128308 200 µg £224     
Product Details
Clone: HMD1-3
Isotype: Armenian Hamster IgG
Isotype Control:PE Armenian Hamster IgG Isotype Ctrl
Reactivity: Mouse
Immunogen: CHO cells expressing murine Dll 1
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested
Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤ 1.0 µg/test for FC. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
Enter Lot#:   
Application
References:

1. Moriyama Y, et al. 2008. Int. Immunol. 20:763.
LPS-stimulated BALB/c peritoneal macrophages (Day
LPS-stimulated BALB/c peritoneal macrophages (Day 2) stained with HMD1-3 PE


Compare all formats



Description:

The Notch receptors and their ligands are highly conserved from invertebrates to mammals. The Delta-like 1 (DLL1) is one of the four or five Notch ligands identified. The binding to Notch receptor results in the proteolysis of Notch and movement of intracellular portion of Notch into the nucleus.This translocation triggers a series of signaling process. Delta-like 1 is reported to be essential for the maintenance of marginal zone B cells in normal mice, and engagement of Notch 1 by DLL1 promotes differentiation of B lymphocytes to antibody-secreting cells.
Other Names: Dll 1, Dll-1
Structure: A single pass transmembrane protein consisting of a large extracellular N-terminal which includes the DSL domain, followed by a tandem array of EGF-like repeats (ELRs). After a single transmembrane domain (TM) is a novel intracellular domain.
Function: The Notch receptors and their ligands are highly conserved signaling molecules throughout development. They regulate cell fate decision for various cell development, including myogenesis, neurogenesis, and lymphocyte development.
Ligand Receptor: Notch receptors
Antigen
References:

1. Ehebauer MT, et al. 2006. Biochem. J. 392:13.
2. Shimizu K, et al. 2000. Mol. Cell. Biology 20:18.
3. Parks AL, et al.2006. Genetics 174:1947.
4. Santos MA, et al. 2007. P. Natl. Acad. Sci. USA 104:15454.
GeneID: 13388
Latest Publications: View the latest Delta Like-1 articles on HighwirePress.com
UniProt: View information about Delta Like-1 on UniProt.org
Keywords: PE anti-mouse DLL1, HMD1-3, PE, Dll 1, Dll-1 , Mouse, Immunology, Antibodies
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Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
  • Purified anti-mouse DLL1
    FD1/CHO (mouse DLL1 transfected cel

    FD1/CHO (mouse DLL1 transfected cel l line) stained with purified HMD1-3, followed by anti-Armenian hamster IgG PE

  • Biotin anti-mouse DLL1
    FD1/CHO transfected cells stained with

    FD1/CHO transfected cells stained with HMD1-3 biotin, followed by Sav-PE

  • LEAF™ Purified anti-mouse DLL1
    FD1/CHO transfected cells stained with

    FD1/CHO transfected cells stained with LEAF™ purified HMD1-3, followed by anti-Armenian Hamster IgG-PE

  • PE anti-mouse DLL1
    LPS-stimulated BALB/c peritoneal macrophages (Day

    LPS-stimulated BALB/c peritoneal macrophages (Day 2) stained with HMD1-3 PE

  • Alexa Fluor® 647 anti-mouse DLL1
    FD1/CHO (mouse DLL1) transfected cell

    FD1/CHO (mouse DLL1) transfected cell line stained with HMD1-3 Alexa Fluor® 647

  • APC anti-mouse DLL1
    FD1/CHO (mouse DLL1) transfected cell

    FD1/CHO (mouse DLL1) transfected cell line stained with HMD1-3 APC

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