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PE Anti-Human IREM-2 (CD300e, CMRF35-A5) Antibody
Material Safety Data Sheet (MSDS) PE Anti-Human IREM-2 CD300e CMRF35-A5 Antibody     Product Data Sheet (HTML)     Product Data Sheet (PDF)    
PE Anti-Human IREM-2 (CD300e, CMRF35-A5) Antibody
339703 25 tests $140.00     
339704 100 tests $295.00     
Clone: UP-H2
Isotype: Mouse IgG1, κ
Reactivity: Human
Immunogen: IREM-IgG fusion protein
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.
Storage & Handling: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested
IHC (frozen)*, IP*, activation* - *This application has been reported in the literature.

Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 µl per million cells or 20 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Application
Notes:

Additional reported applications include: immunoprecipitation and stimulation of TNF-a production by monocytes

Application
References:

1. Aguilar, H., et al. 2004. J. Immunol. 173: 6703

Human peripheral blood monocytes stained

Human peripheral blood monocytes stained with UP-H2 PE


Description:

IREM-2 (immune receptor expressed by myeloid cells 2), also known as CMRF35-A5, LMIR6, CD300Le or CD300e, is a 34 kDa type I single transmembrane glycoprotein. It is a member of the CD300 family and of the Ig-superfamily. IREM-2 is expressed on monocyte and myeloid dendritic cells, but not on granulocytes and lymphoid dendritic cells. IREM-2 is an activating receptor through interaction with DAP12.

Other Names: CD300e, CMRF35-A5, LMIR6,
Structure: 34 kD, type I transmembrane glycoprotein, CD300 family, Ig superfamily
Distribution: Monocytes, macrophages, dendritic cells
Function: Activation of myeloid cells
Antigen
References:

1. Aguilar, H., et al. 2004. J. Immunol. 173: 6703

PE Mouse IgG1, κ Isotype CtrlMOPC-21FC,ICFC
Cell Staining BufferFC, ICC, ICFC
RBC Lysis Buffer (10X)FC,ICFC
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering/). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
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