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Natural Killer Cells
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Natural Killer (NK) cells were initially named based on the observation that they had cytolytic function in the absence of any specific kind of immunization. NK cells can release a bounty of cytokines and chemokines, including TNF-α, IFN-γ, IL-3, IL-10, GM-CSF, G-CSF, CCL2, CCL3, CCL4, CCL5, XCL1, and CXCL8. Type I IFNs, IL-2, IL-12, IL-15, and IL-18 are all potent activators of NK cells. NK cells are a vital arm of innate immunity and participate in surveillance against viral-infection and tumor cells.

View our: Innate Immunity Pathways
Originating from the thymus, NKT (Natural Killer T) cells represent a combination of T cell and NK cell attributes/markers. They express a T cell receptor (TCR) complex and several NK cell markers. The ability of these cells to produce Th1 and Th2-related cytokines has implicated them in several fields, including transplantation, tumors, autoimmunity, and allergy.

View our: Innate Immunity Pathways
NKT Cells
NK Cells
NK and NKT cells are ready to fight.
BCLXL CD1D CD4 CD4 CD4 CD4 CD4 CD4 CD8 CD24 CD24 CD24 CD69 CD150SLAM FYN IL4 IL4 MHCI MHCII NFKB NK11 NK11 RORGT tbet TCR CD44 CD44 IFNG
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