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BioLegend Natural Killer Cells
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Natural Killer (NK) cells were initially named based on the observation that they had cytolytic function in the absence of any specific kind of immunization. NK cells can release a bounty of cytokines and chemokines, including TNF-α, IFN-γ, IL-3, IL-10, GM-CSF, G-CSF, CCL2, CCL3, CCL4, CCL5, XCL1, and CXCL8. Type I IFNs, IL-2, IL-12, IL-15, and IL-18 are all potent activators of NK cells. NK cells are a vital arm of innate immunity and participate in surveillance against viral-infection and tumor cells.

View our: Innate Immunity Pathways
Originating from the thymus, NKT (Natural Killer T) cells represent a combination of T cell and NK cell attributes/markers. They express a T cell receptor (TCR) complex and several NK cell markers. The ability of these cells to produce Th1 and Th2-related cytokines has implicated them in several fields, including transplantation, tumors, autoimmunity, and allergy.

View our: Innate Immunity Pathways
NKT Cells
NK Cells
NK and NKT cells are ready to fight.
CD44 NK1.1 IL-4 IFN-G BCLXL CD1D CD4 CD4 CD4 CD4 CD4 CD4 CD8 CD24 CD24 CD24 CD69 CD150SLAM FYN IL4 IL4 MHCI MHCII NFKB NK11 NK11 RORGT PKCT tbet TCR CD44 CD44 IFNG
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