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Interleukin-29 (IL-29, IFN-λ1) is a class II cytokine receptor ligand distantly related to type I interferons (IFNs) and the IL-10 family. IL-29 is similar in amino acid sequence to IL-28A (IFN-λ2) and IL-28B (IFN-λ3) as IL-29 shows 81% homology with IL-28A. IL-28 and IL-29 are produced by human peripheral blood mononuclear cells and dendritic cells upon viral infection, LPS stimulation, TLR stimulation, stimulation with poly(I:C) and other inducers of type I IFNs. IL-28 and IL-29 play a role in the IFN-mediated immune defense against viruses and up-regulates MHC class I antigen expression.
BioLegend’s LEGEND MAX™ Human IL-29 ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA), in which, a Human IL-29 specific monoclonal antibody is pre-coated on a 96-well strip-well plate.
BioLegend’s LEGEND MAX™ Human IL-29 ELISA Kit is specifically designed for the accurate quantitation of Human IL-29 from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive. |