Human IL-1β (Interleukin-1β, Catabolin, Hematopoietin-1 (H1), IFN-β-inducing factor, Interleukin-β, Osteoclast activating factor (OAF)). IL-1 refers to two proteins, IL-1α and IL-1β which are the products of distinct genes, but which are recognized by the same cell surface receptors. IL-1β is a potent immuno-modulator which mediates a wide range of immune and inflammatory responses including the activation of B and T cells. IL-1β is expressed in several cell types, including monocytes, tissue macrophages, Langerhan cells, dendritic cells, T lymphocytes, B lymphocytes, and natural killer cells. IL-1 β is upregulated by TNF-α, IFN-α, IFN-β, IFN-γ, bacterial endotoxins, viruses, mitogens, and antigens; while IL-1β is downregulated by IL-6, lipoproteins, lipids, and α2-macroglobulin. IL-1 β plays a role in many physiological and pathological conditions including rheumatoid arthritis and cancer.

BioLegend’s LEGEND MAX™ Human IL-1β ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA), in which, a Human IL-1β specific monoclonal antibody is pre-coated on a 96-well strip-well plate.

BioLegend’s LEGEND MAX™ Human IL-1β ELISA Kit is specifically designed for the accurate quantitation of Human IL-1β from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive.