Antibodies
Account Login LEGENDClub
Search 
 
Products Site Search
Advanced Search Shopping Cart
Home Company Products Custom Assays Pathways Support Contact

LEGEND MAX™ Human IL-17A ELISA Kit
Material Safety Data Sheet (MSDS) Legend-max-human-il-17a-elisa-kit     Product Data Sheet (HTML)     Product Data Sheet (PDF)    
LEGEND MAX™ Human IL-17A ELISA Kit
433907 1 Pre-coated Plate $350.00     
433908 5 Pre-coated Plates $1,250.00     
Application: ELISA (Click on the Product Data Sheet (PDF) for typical data and product manual)





Description:

IL-17 or IL-17A originally identified as cytotoxic T lymphocyte-associated antigen-8 (CTLA-8) in mouse, is a founding member of the IL-17 family of cytokines. IL-17 is mainly produced by a small subset of T helper cells called TH17 cells. IL-17 is a 155 amino acid protein that is a disulfide linked, homodimeric, secreted glycoprotein with a molecular mass of 35 kDa. The amino acid sequence of human IL-17 is 63% and 58% identical to mouse and rat IL-17, respectively, and 72% identical to the ORF13 of Herpesvirus saimiri. IL-17 exhibits multiple biological activities including the induction of various proinflammatory cytokines and chemokines such as IL-6, IL-8, G-CSF, GM-CSF, GRO- α, and MCP-1 on a variety of cell types. IL-17 is also involved in the activation of NF-kB and costimulation of T cell proliferation. As a result of these roles, IL-17 has been linked to many immune/autoimmune related diseases including rheumatoid arthritis, asthma, lupus and multiple sclerosis.

BioLegend’s LEGEND MAX™ Human IL-17A ELISA Kit is a sandwich Enzyme-Linked Immunosorbent Assay (ELISA), in which, a Human IL-17A specific monoclonal antibody is pre-coated on a 96-well strip-well plate.

BioLegend’s LEGEND MAX™ Human IL-17A ELISA Kit is specifically designed for the accurate quantitation of Human IL-17A from cell culture supernatant, serum, plasma or other bodily fluids. It is ready-to-use, accurate, and sensitive.

Other Names: IL-17A Pre-coated ELISA Kit ,