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FITC anti-mouse TCR Vδ4 Antibody
FITC anti-mouse TCR Vδ4 Antibody
134903 25 µg $55.00     
134904 100 µg $95.00     
Product Details
Clone: GL2
Isotype: Armenian hamster IgG2, κ
Isotype Control:FITC Armenian Hamster IgG Isotype Ctrl
Reactivity: Mouse
Immunogen: G57BL/6 mouse intestinal intra-epithelial lymphocytes
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC and unconjugated antibody.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.25 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
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Application
References:

1. Lefrancois L, et al. 1990. Cell. 66:33
2. Sperling AI, et al. 1992. J. Immunol. 149(10):3200
3. Pereira P, et al. 1997. Proc. Natl. Acad. Sci. USA. 94:5761
C57BL/6 lymph node cells stained
C57BL/6 lymph node cells stained with GL2 FITC and CD3e (145-2C11) APC

C57BL/6 lymph node cells stained
C57BL/6 lymph node cells stained with Armenian Hamster IgG (HTK888) FITC isotype control and CD3e (145-2C11) APC


Compare all formats



Description:

Lymphocytes expressing γ/δ antigen receptors constitute a minor population in lymphoid tissue, but a major population within epidermal, gastraintestine, and vaginouterine epithelia. Gamma/Delta T cells are involved in immunological surveillance of epithelia separating the external environment from the internal milieu. The GL2 antibody reacts with Vδ4 T-cell receptor (TCR) bearing T cells, which are the predominant γ/δ T cells in intestinal epithelium (γ/δ IEL). Gamma/delta T cells has been found in mammary glad as well. The frequency of Vδ4 TCR-bearing cells varies among inbred strains of mice.
Other Names: T cell receptor Vδ4
Structure: Form heterodimer with TCR gamma chain, associate with CD3 complex.
Distribution: Expressed on Vδ4 T-cell receptor (TCR) bearing T cells, which are predominant γ/δ T cells in intestinal epithelium.
Function: Involved in immunological surveillance of epithelia separating the external environment from internal milieu.
Ligand Receptor: Antigen peptide bound to MHC molecule
Antigen
References:

1. Reardon C, et al. 1990. J. Exp. Med. 172:1263
2. Goodman T, et al. 1989. J. Exp. Med. 170:1569
GeneID: 110066
Latest Publications: View the latest TCR V delta 4 articles on HighwirePress.com
UniProt: View information about TCR V delta 4 on UniProt.org
Keywords: FITC anti-mouse TCR Vδ4, GL2, FITC, T cell receptor Vδ4 , Mouse, Immunology, Antibodies
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Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
  • PE anti-mouse TCR Vδ4
    C57BL/6 lymph node cells stained

    C57BL/6 lymph node cells stained with GL2 PE and CD3e (145-2C11) APC

    C57BL/6 lymph node cells stained

    C57BL/6 lymph node cells stained with Armenian Hamster IgG (HTK888) PE isotype control and CD3e (145-2C11) APC

  • FITC anti-mouse TCR Vδ4
    C57BL/6 lymph node cells stained

    C57BL/6 lymph node cells stained with GL2 FITC and CD3e (145-2C11) APC

    C57BL/6 lymph node cells stained

    C57BL/6 lymph node cells stained with Armenian Hamster IgG (HTK888) FITC isotype control and CD3e (145-2C11) APC

  • Purified anti-mouse TCR Vδ4
    C57BL/6 lymph node cells stained

    C57BL/6 lymph node cells stained with GL2 PE and CD3e (145-2C11) APC

    C57BL/6 lymph node cells stained

    C57BL/6 lymph node cells stained with Armenian Hamster IgG (HTK888) PE isotype control and CD3e (145-2C11) APC

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