Antibodies
      
 
Product Search  
 
FITC anti-mouse TCR γ/δ Antibody
Cat. # Size Price  

107503 50 µg $75.00
    
107504 500 µg $250.00
    
Product Details

Clone: UC7-13D5 (See other available formats)
Isotype: Armenian Hamster IgG
Isotype Control:FITC Armenian Hamster IgG Isotype Ctrl
Reactivity: Mouse
Formulation: Tris-buffered solution pH 8.0, containing 0.09% sodium azide
Preparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation
Laser:
Blue Laser (488 nm)
Application
Notes:
Additional reported applications (for the relevant formats) include: immunoprecipitation1, in vitro stimulation1,2,4 and in vivo depletion3-5. The LEAF™ purified antibody (Endotoxin <0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 107506).
Application
References:
  Publication Library
 Image 1
C57BL/6 splenocytes stained with CD3 (145-2C11) APC and UC7-13D5 FITC


Compare all formats

See FITC spectral data





 


Antigen Details

Description: T cell receptor (TCR) is a heterodimer consisting of an α and a β chain (TCR α/β) or a γ and a δ chain (TCR γ/δ). TCR γ/δ belongs to the immunoglobulin superfamily, involved in the recognition of certain bacterial and tumor antigens bound to MHC class I. The TCR γ/δ associates with CD3 and is expressed on a T cell subset found in the thymus, the intestinal epithelium, and the peripheral lymphoid tissues and peritoneum. Most γ/δ T cells are CD4-/CD8-, some are CD8+. T cells expressing the TCR γ/δ have been shown to play a role in oral tolerance, tumor-associated tolerance, and autoimmune disease. It has been reported that γ/δ T cells also play a principal role in antigen presentation. Immobilized UC7-13D5 antibody has been reported to activate TCR-γ/δ-bearing T cells in vitro, and to deplete peripheral TCR-γ/δ-bearing T cells in vivo.
  Learn more about TCR γ/δ nomenclature.

Other Names: TCR-γ/δ, γ/δ TCR
Structure: Ig superfamily, associates with CD3 complex
Distribution: T subset in thymus, intestinal epithelium, peripheral lymphoid tissues and peritoneum
Function: Antigen recognition
Ligand Receptor: Some bacterial or tumor antigens bound MHC class I
Antigen
References:
1. Skarstein K, et al. 1995. Immunology 81:497.
2. Harrison LC, et al. 1996. J. Exp. Med. 184:2167.
3. Wildner G, et al. 1996. Eur. J. Immunol. 26:2140.
4. Brandes M, et al. 2005. Science 309:264.
GeneID: 110066
110067
UniProt: View information about TCR gamma/delta on UniProt.org
Keywords: FITC anti-mouse TCR γ/δ, UC7-13D5, FITC, TCR-γ/δ, γ/δ TCR, Mouse, Flow Cytometry, Immunology, Antibodies
Technical Data Sheet (pdf)
Material Safety Data Sheet
Certificate of Analysis
Request Bulk Quote
Request Custom Conjugation
Email Technical Support
Write a Review
View All TCR γ/δ Reagents
Related Protocols

Cell Surface Immunofluorescence Staining Protocol
Related Pages

Multicolor Panel Selector
Fluorescence Spectra Analyzer
Fluorophore Brightness Index
Custom Panel Construction
Fluorophore Equivalency Tool
Flow Cytometry Mobile Application
Fluorescence Spectra Analyzer Mobile Application
Rating

This product has not been reviewed yet.

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

Version: 2 Revision Date: 2013-11-19
x
Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.

  • FITC anti-mouse TCR γ/δ
    C57BL/6 splenocytes stained with CD3

    C57BL/6 splenocytes stained with CD3 (145-2C11) APC and UC7-13D5 FITC

  • Purified anti-mouse TCR γ/δ
    C57BL/6 splenocytes stained with 17A2

    C57BL/6 splenocytes stained with 17A2 (CD3) APC and purified UC7-13D5, followed by anti-Armenian hamster IgG PE

  • PE anti-mouse TCR γ/δ
    C57BL/6 mouse lymph node cells

    C57BL/6 mouse lymph node cells stained with 145-2C11 APC and UC7-13D5 PE

  • Alexa Fluor® 488 anti-mouse TCR γ/δ
    C57BL/6 mouse splenocytes stained with

    C57BL/6 mouse splenocytes stained with CD3 (17A2) PE and UC7-13D5 Alexa Fluor® 488

x
x
*Your Rating:
*Your Comment:
*Name (first, last):
*Affiliation:
*Email:
*Required fields
Note: Submission of a quick review does not qualify for our promotional $25 Amazon gift card. A full review submission is required for gift card eligibility.

Learn more…
9727 Pacific Heights Blvd.
San Diego, CA 92121

Tel: 858.768.5800
Company
Careers
Promotions
Web Tools
Areas of Biology
Pathways
Products
Literature
Custom Products/Services
Custom Panel Construction
Technical Support
Support Resources
Ordering
Contact
Distributors
Sitemap
Connect with us:

Facebook Twitter Pinterest LinkedIn YouTube Tumblr Blog Podcast
The LEGENDeers Pandora Google+ Wikipedia RSS Feed Arcade Words With Elements Satisfaction Survey
Privacy Policy | Terms
World-Class Quality | Superior Customer Support | Outstanding Value Copyright © 2014 BioLegend, Inc. All rights reserved.
Product Search