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FITC anti-mouse CD199 (CCR9) Antibody
FITC anti-mouse CD199 (CCR9) Antibody
128705 50 µg $100.00     
128706 500 µg $310.00     

Product Details

Clone: CW-1.2
Isotype: Mouse IgG2a, κ
Isotype Control:FITC Mouse IgG2a, κ Isotype Ctrl
Reactivity: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Application: FC - Quality tested
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤ 0.25 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
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C57BL/6 thymocytes stained with CW-1.2
C57BL/6 thymocytes stained with CW-1.2 FITC


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Description:

CCR9 is a member of the G protein coupled receptor family and is involved in T cell development in the thymus and in gut-associated immune response. Mouse CCR9 is highly expressed on different stages of thymocytes and upregulated on CD4+CD8+ cells. It is expressed to a much lower level on spleen and lymph node cells. Expression of CCR9 on γ/δ T cells in the intraepithelial and small intestine has been reported. The interaction of CCR9 with its ligand CCL25 (TECK, thymus-expressed chemokine) may direct the trafficking of developing T cells in the thymus and generation of gut-specific immunological memory. 

Other Names: GPR 9-6, CDw199, Chemokine Receptor 9
Structure: A membrane of G-protein coupled receptors and contains seven transmembrain domains. Mouse CCR9 has above 80% amino acid sequence homology with human counterpart.
Distribution: CD4+CD8+ thymocytes, γ/δ T cells
Ligand Receptor: CCL25
Interaction: CCL25
Antigen
References:

1. Zaballos A, et al. 1999. J. Immunol. 162:5671.
2. Wurbel MA, et al. 2007. J. Immunol. 178:7598.
3. Wurbel MA, et al. 2006. Eur. J. Immunol. 36:73.

GeneID: 12769
Latest Publications: View the latest CD199 articles on HighwirePress.com
UniProt: View information about CD199 on UniProt.org
Keywords: FITC anti-mouse CD199 (CCR9), CW-1.2, FITC, GPR 9-6, CDw199, Chemokine Receptor 9, Mouse, Immunology, Antibodies
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Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.

  • Purified anti-mouse CD199 (CCR9)
    C57BL/6 thymocytes stained with CW-1.2

    C57BL/6 thymocytes stained with CW-1.2 purified, followed by anti-mouse IgG2a FITC

  • FITC anti-mouse CD199 (CCR9)
    C57BL/6 thymocytes stained with CW-1.2

    C57BL/6 thymocytes stained with CW-1.2 FITC

  • Alexa Fluor® 647 anti-mouse CD199 (CCR9)
    C57BL/6 thymocytes stained with CW-1.2

    C57BL/6 thymocytes stained with CW-1.2 Alexa Fluo® 647

  • PE/Cy7 anti-mouse CD199 (CCR9)
    C57BL/6 mouse thymocytes were stained

    C57BL/6 mouse thymocytes were stained with CCR9 (clone CW-1.2) PE/Cy7 (filled histogram) or mouse IgG2a, κ PE/Cy7 isotype control (open histogram).

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