Antibodies
Search 
 
Products Site Search
Advanced Search Login Cart
Home Company Products Web Tools Pathways Support Contact

FITC Anti-human CD59 Antibody
Material Safety Data Sheet (MSDS) FITC Anti-human CD59 Antibody     Product Data Sheet (HTML)     Product Data Sheet (PDF)    
FITC Anti-human CD59 Antibody
304706 100 tests $195.00     
Clone: p282 (H19)
Isotype: Mouse IgG2a, κ
Workshop
Number:
V S006
Reactivity: Human, Cross-Reactivity*: Chimpanzee, Baboon, Cynomolgus, Rhesus
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation: The antibody was purified by affinity chromatography, and conjugated with FITC under optimal conditions. The solution is free of unconjugated FITC.
Storage & Handling: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Application: FC
Recommended Usage: Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 20 µl per million cells or 20 µl per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.
Application
References:
1. Schlossman, S., et al., Eds. 1995. Leucocyte Typing V. Oxford University Press. New York.
Human peripheral blood lymphocytes stained
with

Human peripheral blood lymphocytes stained with p282(H19) FITC


Description: CD59 is a 19-25 kD glycosylphosphatidylinositol (GPI)-anchored glycoprotein also known as protectin, MACIF, and H19. It is broadly expressed on hematopoietic and non-hematopoietic cells. CD59 inhibits the cytolytic activity of complement by binding to C9, inhibiting incorporation into C5b-8, and preventing the terminal steps in complement polymerization of the membrane attack complex. CD59 has also been reported to play a role in T cell activation.
Other Names: Protectin, H19, 1F-5Ag, HRF20, MACIF, MIRL, P-18
Structure: Ly6 superfamily, single chain GPI-linked membrane protein, 19-25 kD
Distribution: All cell types
Function: Blocks complement-mediated lysis by inhibiting MAC formation
Ligand Receptor: Complement components C8, C9
Antigen
References:
1. Davies, A., et al., 1993. Immunol. Res. 12:258.
2. Lachmann, P. 1991. Immunol. Today 12:312.
3. Liszewski, M., et al., 1996. Adv. Immunol. 61:201.
FITC Mouse IgG2a, κ Isotype CtrlMOPC-173FC,ICFC
Cell Staining BufferFC, ICC, ICFC
RBC Lysis Buffer (10X)FC,ICFC
FITC anti-human CD55JS11FC
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/ordering/). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
BioLegend - Home | Company |  Products | Pathways |  Support | Ordering |  Careers | Contact |  Distributors | Sitemap |     
Copyright © 2010 BioLegend, Inc. All rights reserved.