Welcome to BioLegend's interactive Cell Markers page. Find out what markers are expressed on your cell type of interest and then find products suitable for your applications. Learn, Discover, Become a Legend…
*This page may take a minute or more to download due to the rich content. Thank you for your patience.
|
 | x |
|
Basophil
|
 | x |
|
B Cell
|
 | x |
|
Embryonic Stem Cell
Embryonic stem cells are pluripotent stem cells capable of developing into any one the 220 different cell types found in the human body. They are derived from the inner mass of embryos at the blastocyst stage, 4-5 days post-fertilization. Related PathwaysStem Cells & Development
|
 | x |
|
Endothelial Cell
|
 | x |
|
Eosinophil
|
 | x |
|
Epithelial Cell
|
 | x |
|
Erythrocyte
|
 | x |
|
Fibroblast
Fibroblasts are cells of mesenchymal origin that produce extracellular matrix and collagen, which are materials that provide 3-dimensional structure for animal tissues and organs. Fibroblast are important for wound healing and are the most common cell type found in the connective tissues in animals. In stem cell research, mouse embryonic fibroblast are commonly used as "feeder" cells to help maintain human embryonic stem cells. Related PathwaysImmunologic NetworksStem Cells & DevelopmentTH2 Pathway (Humoral Immune Response)TH17 Pathway
|
 | x |
|
Hematopoietic Stem Cell
Hematopoietic stem cells (HSCs) are bone marrow-derived multipotent stem cells that give rise to all the blood cell types from the myeloid (monocytes and macrophages, neutrophils, basophils, eosinophils, erythrocytes, megakaryocytes/platelets, dendritic cells), and lymphoid lineages (T, B, and NK cells). The hematopoietic tissue contains a heterogenous population of cells with long-term and short-term regeneration capacities and committed multipotent, oligopotent, and unipotent progenitors. HSCs constitute 1:10,000 of cells in myeloid tissue. HSCs are critical for the repopulation of patients' blood cells in bone marrow transplantation. Related PathwaysHematopoiesis from Multipotent Stem CellStem Cells & Development
|
 | x |
|
Macrophage
|
 | x |
|
Mast Cell
Mast cells are tissue resident cells that are most well-known for their role in allergy, autoimmunity, and anaphylaxis, but also have important roles in wound healing and pathogen defenses. Mast cells contain many granules full of inflammatory factors including histamine, heparin, and lipid mediators, such as thromboxane, prostaglandin D2, and leukotriene C4, as well as other factors. Mast cells degranulate upon stimulation by direct physical injury or chemical injury, cross-linking of Immunoglobulin E (IgE) receptors, or by activated complement proteins. Related PathwaysChemokine Receptor BiologyCytokine Networksγδ T CellImmunologic NetworksRegulatory T Cell DevelopmentStem Cells & DevelopmentTH2 Pathway (Humoral Immune Response)
|
 | x |
|
MDSC
Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of cells that have potent T cell-suppressive function, characterized by an activated state with increased production of reactive oxygen and nitrogen species, and arginase 1. In mice, the phenotype of MDSCs is CD11b+GR1+, while in humans, the phenotype of MDSCs is LIN–HLA-DR–CD33+ or CD11b+CD14–CD33+. Tumors have have been shown to hijack the suppressive capacity of MDSCs and use them to escape T cell killing, in order to promote tumor survival and expansion. Related PathwaysMyeloid-Derived Suppressor CellsCancer Immunoediting
|
 | x |
|
Megakarocyte
Megakaryocytes are blood cells that produce platelets (thrombocytes), which are required for normal blood clotting. In the bone marrow, megakaryocytes are quite rare, accounting for only 1 in 10,000 white blood cells. The primary signal for megakaryocyte production is thrombopoietin (TPO), although other factors can induce differentiation of progenitor cells in the bone marrow towards a final megakaryocyte phenotype, including GM-CSF, IL-3, IL-6, IL-11, chemokines (SDF-1 ; FGF-4), and erythropoietin. When the cell reaches megakaryoblast stage, it loses its ability to divide. However, it is still able to replicate its DNA and continue development, becoming polyploid, up to 64N, while the cytoplasm continues to expand. Related PathwaysHematopoiesis from Multipotent Stem CellHematopoiesis from Pluripotent Stem CellStem Cells & Development
|
 | x |
|
Mesenchymal Stem Cell
Mesenchymal stem cells, or MSCs, are multipotent stem cells derived from the mesoderm that can differentiate into a variety of cell types, including: osteoblasts, chondrocytes, myocytes, adipocytes, and even β-pancreatic islet cells. While hematopoietic stem cells are also derived from the mesoderm, mesenchymal stem cells are committed to a non-hematopoietic path and cannot differentiate into blood cells. Due to their multipotency, MSCs are now widely studied to determine their possible utility in tissue engineering, wound healing, diabetes, and other conditions in which regenerated cells can improve or resolve disease. Related PathwaysStem Cells & Development
|
 | x |
|
Myeloid Dendritic Cell
|
 | x |
|
Neutrophil
|
 | x |
|
NK Cell
|
 | x |
|
Plasmacytoid Dendritic Cell
|
 | x |
|
Naive T Cell
|
 | x |
|
Th1
|
 | x |
|
Th2
|
 | x |
|
Th17
|
 | x |
|
Treg
|
|
