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The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions. The solution is free of unconjugated biotin.
Concentration:
0.5 mg/ml
Storage & Handling:
The antibody solution should be stored undiluted at 4°C. Do not freeze.
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. Test size products are transitioning from 20 µl to 5 µl per test. Please check your vial or your CoA to find the suggested use of this reagent per million cells in 100 µl staining volume or per 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application. Read more at www.biolegend.com/testsize regarding the test size change.
COA:
CXCR7 transfected mouse L1.2 cells stained with biotinylated 8F11-M16, followed by Sav-PE
CXCR7, also known as RDC1, belongs to a subgroup of C-X-C chemokine receptors, which are part of a large protein family of G protein-coupled receptors (GPCR). CXCR7 binds with high-affinity to CXCL12/SDF-1 and CXCL11/I-TAC, which regulates the trafficking and activation of leukocytes. It is also a co-receptor for the entry of HIV-1. Binding of ligand to CXCR7 induces proliferation and migration of immature neurons, glia and their precursors. CXCR7 expression occurs on a wide variety of tissues and cells including monocytes, B cells, T cells and mature dendritic cells. Surface expression of CXCR7 was also reported to be on tumor cells, activated endothelial cells, fetal liver cells, and few other cell types.
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
Purified anti-human/mouse CXCR7
CXCR7 transfected mouse L1.2 cells stained with purified 8F11-M16, followed by anti-mouse IgG PE
LEAF™ Purified anti-human/mouse CXCR7
CXCR7 transfected mouse L1.2 cells stained with LEAF™ purified 8F11-M16, followed by anti-mouse IgG PE
PE anti-human/mouse CXCR7
CXCR7 transfected mouse L1.2 cells stained with 8F11-M16 PE
Biotin anti-human/mouse CXCR7
CXCR7 transfected mouse L1.2 cells stained with biotinylated 8F11-M16, followed by Sav-PE
APC anti-human/mouse CXCR7
CXCR7 transfected L1.2 cells were stained with CXCR7 (clone 8F11-M16) APC (filled histogram) or mouse IgG2b APC isotype control (open histogram).
