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APC anti-mouse TCR Vγ3 Antibody
APC anti-mouse TCR Vγ3 Antibody
137505 25 µg $125.00     
137506 100 µg $285.00     
Product Details
 
Clone: 536 (See other available formats)
Isotype: Syrian hamster IgG
Isotype Control:APC Syrian Hamster IgG Isotype Ctrl
Reactivity: Mouse, Cross-Reactivity: No
Immunogen: AKR mouse dendritic epidermal cell clone 7-17
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested
Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤0.5 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
Excitation
Laser: 		Red Laser (633 nm)
COA:
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Application
Notes:

Additional reported (for relevant formats) application include: immunoprecipitation1 and immunofluorescence2.

This product may be used for research purposes only. It is not licensed for resale and may only be used by the buyer. This product may not be used and is not licensed for clinical assays, where the results of such assays are provided as a diagnostic service. If a diagnostic or therapeutic use is anticipated, then a license must be requested from the University of California. This availability of such diagnostic and therapeutic use license(s) cannot be guaranteed from the University of California.
Application
References:

  Publication Library
APC anti-mouse TCR Vγ3 Antibody 536 Image 1
Mouse dendritic epidermal cell line 7-17 were stained with anti-mouse TCR Vγ3 (clone 536) APC (filled histogram) or hamster IgG APC isotype control (open histogram).


Compare all formats

See APC spectral data



Description:

Vγ3+ T cells are the predominant γδ TCR-bearing cells in early fetal thymus.  The majority of CD3+ cells in 14-day fetal thymus express Vγ3.   Vγ3 is also expressed on Thy-1+ dendritic epidermal cells (Thy-1+ DECs).  Cells that express Vγ3 are not significantly detectable in adult lymphoid organs.  It has been reported that Lck and Fyn, two Src family kinases, are required for the development of Vγ3+ T cells.
  Learn more about TCR γ/δ nomenclature.
Other Names: Vγ3 T-cell receptor, T cell receptor gamma 3
Structure: A member of Ig superfamily, heterodimerized with δ TCR chain and associated with CD3 complex.
Distribution: Dendritic epidermal T cells (DECs) and fetal murine thymocytes.
Function: Antigen recognition
Ligand Receptor: Antigens
Antigen
References:

1. Allison JP, et al. 1991. Annu. Rev. Immunol. 9:679.
2. O’Brien RL, et al. 2000. J. Immunol. 165:6472.
3. Kelly KA, et al. 1993. Int Immunol. 5:331.
4. Moore TA, et al. 1996. J. Immunol. 157:2366.
5. Payer E, et al. 1991. J. Immunol. 146:2536.
6. Van Oers NSC, et al. 1996. Immunity 5:429.
GeneID: 110067
Latest Publications: View the latest TCR V gamma 3 articles on HighwirePress.com
UniProt: View information about TCR V gamma 3 on UniProt.org
Keywords: APC anti-mouse TCR Vγ3, 536, APC, Vγ3 T-cell receptor, T cell receptor gamma 3 , Mouse, Cross-Reactivity: No, Flow Cytometry, Immunology, Antibodies
Related Products
DescriptionCloneApplications
APC Syrian Hamster IgG Isotype CtrlSHG-1FC, ICFC
Cell Staining BufferFC, ICC, ICFC
RBC Lysis Buffer (10X)FC, ICFC
TruStain fcX™ (anti-mouse CD16/32)93 FC


Other Formats
DescriptionCloneApplications
PE anti-mouse TCR Vγ3536FC
Purified anti-mouse TCR Vγ3536FC, IP, IF
*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

Version: 1 Revision Date: 2012-11-30
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Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
  • Purified anti-mouse TCR Vγ3
    Mouse dendritic epidermal cell line

    Mouse dendritic epidermal cell line 7-17 stained with purified 536 conjugated with PE

  • PE anti-mouse TCR Vγ3
    Mouse dendritic epidermal cell line

    Mouse dendritic epidermal cell line 7-17 stained with 536 PE

  • APC anti-mouse TCR Vγ3
    Mouse dendritic epidermal cell line

    Mouse dendritic epidermal cell line 7-17 were stained with anti-mouse TCR Vγ3 (clone 536) APC (filled histogram) or hamster IgG APC isotype control (open histogram).

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