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APC anti-mouse CD79a (Igα) Antibody
APC anti-mouse CD79a (Igα) Antibody
133105 25 µg $110.00     
133106 100 µg $275.00     
Product Details
Clone: F11-172
Isotype: Armenian Hamster IgG1
Isotype Control:APC Armenian Hamster IgG Isotype Ctrl
Reactivity: Mouse
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography, and conjugated with APC under optimal conditions. The solution is free of unconjugated APC and unconjugated antibody.
Concentration: 0.2 mg/ml
Storage & Handling: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Application:

ICFC - Quality tested
Recommended Usage:

Each lot of this antibody is quality control tested by intracellular immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is ≤ 1.0 µg per 106 cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.
COA:
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Application
References:

1. Kraus M, et al. 2001. J. Exp. Med. 194:455
C57BL/6 splenocytes stained with B220
C57BL/6 splenocytes stained with B220 (RA3-6B2) PE and F11-172 APC


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Description:

Mouse CD79a (Ig α chain) is a 47 kD type I integral membrane protein, known as mb-1 or Ig α. It forms a heterodimer with CD79b (Ig β chain). The CD79a and CD79b heterodimers are associated with surface IgM to form the B-cell receptor (BCR) that is necessary for signal transduction via the BCR in mature B cells. CD79a may play a role in mediating the transport of IgM to the cell surface. Clone F11-172 antibody recognizes the 47 kD membrane glycoprotein present on B lymphocytes.
Other Names: Mb-1, Igα
Structure: A 47 kD membrane glycoprotein which associates with CD79b to form part of B-cell receptor complex.
Distribution: CD79a is expressed on B cells at various differentiation stages, from pre-B cell to plasma cells. It is expressed probably before expression of cytoplasmic µu chain.
Function: Mediating the transport of IgM to the cell surface.
Ligand Receptor: CD79a/CD79b heterodimers are associated with surface IgM to form B cell receptor complex (BCR) to recognize specific antigen.
Antigen
References:

1. Schamel W, et al. 2000. Immunity 13:5
2. Taddie JA, et al. 1994. J. Biol. Chem. 269:13529
GeneID: 12518
Latest Publications: View the latest CD79a articles on HighwirePress.com
UniProt: View information about CD79a on UniProt.org
Keywords: APC anti-mouse CD79a (Igα), F11-172, APC, Mb-1, Igα, Mouse, Immunology, Antibodies
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Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
  • PE anti-mouse CD79a (Igα)
    C57BL/6 mouse splenocytes were intracellular

    C57BL/6 mouse splenocytes were intracellular stained with F11-172 PE

  • APC anti-mouse CD79a (Igα)
    C57BL/6 splenocytes stained with B220

    C57BL/6 splenocytes stained with B220 (RA3-6B2) PE and F11-172 APC

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