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Alexa Fluor® 647 anti-human STRO-1 Antibody
Alexa Fluor® 647 anti-human STRO-1 Antibody
340103 25 tests $140.00     
340104 100 tests $315.00     
Product Details
Clone: STRO-1
Isotype: Mouse IgM, λ
Isotype Control:Alexa Fluor® 647 Mouse IgM, κ Isotype Ctrl
Reactivity: Human
Immunogen: Human CD34+ bone marrow cells
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA (origin USA).
Preparation: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions. The solution is free of unconjugated Alexa Fluor® 647.
Storage & Handling: The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Application:

FC - Quality tested
Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For immunofluorescent staining, the suggested use of this reagent is 5 µl per 106 cells in 100 µl volume or 100 µl of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

* Alexa Fluor® 647 has a maximum emission of 668 nm when it is excited at 633nm / 635nm.
** Alexa Fluor® 647 is a registered trademark of Molecular Probes, Inc. Alexa Fluor® 647 dye antibody conjugates are sold under license from Molecular Probes, Inc. for research use only, except for use in combination with microarrays and high content screening, and are covered by pending and issued patents.



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COA:
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Application
References:

1. Simmons PJ and B. Torok-Storb 1991. Blood 78:55.
Human osteosarcoma cell line (MG-63)
Human osteosarcoma cell line (MG-63) were stained with STRO-1 Alexa Fluor® 647 (red histogram), or mouse IgM, λ Alexa Fluor® 647 (green histogram).


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Description:

STRO-1 is a cell surface antigen recognized by mAb STRO-1. It is expressed by bone marrow mesenchymal stromal cells and nucleated erythroid precursors, but not by committed hematopoietic progenitors. In combination with glycophorin A (GPA), STRO-1 is a useful marker for identification of mesenchymal stem cells. It has been reported that STRO-1+/GPA- bone marrow cell subset can be used as a universal stromal feeder layer for hematopoietic stem/progenitor cells. This subset of cells has multipotent to differentiate into fibroblasts, adipocytes, osteoblasts, chondrocytes, and vascular smooth muscle-like cells.
Distribution: Mesenchymal stromal cells, nucleated erythroid precursors
Antigen
References:

1. Simmons PJ and B. Torok-Storb 1991. Blood 78:55.
2.Stewart K, et al. 1999. Bone Miner Res. 14:1345.
3. 3. Dennis JE, et al. 2002. Cell Tissues Organs 170:73.
4.Goncalves R, et al. 2006. Exp. Hematol. 34:1353.
GeneID: NA
Latest Publications: View the latest STRO-1 articles on HighwirePress.com
UniProt: View information about STRO-1 on UniProt.org
Keywords: Alexa Fluor® 647 anti-human STRO-1, STRO-1, Alexa Fluor® 647, Human, Immunology, Antibodies
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*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, www.biolegend.com/terms). BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.
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Compare Data Across All Formats
This data display is provided for general comparisons between formats. Your actual data may vary due to variations in samples, target cells, instruments and their settings, staining conditions, and other factors. If you need assistance with selecting the best format contact our expert technical support team.
  • Alexa Fluor® 647 anti-human STRO-1
    Human osteosarcoma cell line (MG-63)

    Human osteosarcoma cell line (MG-63) were stained with STRO-1 Alexa Fluor® 647 (red histogram), or mouse IgM, λ Alexa Fluor® 647 (green histogram).

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