Purified anti-mouse CD371 (CLEC12A) Antibody
Purified anti-mouse CD371 (CLEC12A) Antibody
143401 25 µg $85.00 Qty:
143402 100 µg $185.00 Qty:

Product Details

Clone: 5D3/CLEC12A (See other available formats)
Isotype: Rat IgG2a, κ
Isotype Control:Purified Rat IgG2a, κ Isotype Ctrl
Reactivity: Mouse
Immunogen: CHO expressing mouse CLEC12A
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.

FC - Quality tested

Recommended Usage:

Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤1.0 µg per million cells in 100 µl volume. It is recommended that the reagent be titrated for optimal performance for each application.

Enter Lot#:   

Cell Surface Immunofluorescence Staining Protocol


CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family.  Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases. Mouse CLEC12A is expressed on CD8+ dendritic cells (DCs), a proportion of CD8- dendritc cells, plasmacytoid DCs, monoctyes, macrophages, granulocytes, and B cells.

Other Names: CLL1, MICL, CLL-1, DCAL-2, C-type lectin domain family 12 member A, CD371
Structure: Type II C-type lectin family member, 265 aa, 30.7 kD
Distribution: CD8+ dendritic cells (DCs), a proportion of CD8- dendritic cells, plasmacytoid DCs, monocytes, macrophages, granulocytes, B cells
Function: Negative regulator of granuocyte and monocyte function
Interaction: PTPN6 and PTPN11

1. Lahoud MH, et al. 2009. J. Immunol. 182:7587.
2. Chen CH, et al. 2006. Blood 107:1459.
3. Marshall AS, et al. 2004. J. Biol. Chem. 279:14792.

GeneID: 232413
Latest Publications: View the latest CD371 articles on
UniProt: View information about CD371 on
Keywords: Purified anti-mouse CD371 (CLEC12A), 5D3/CLEC12A, Purified, CLL1, MICL, CLL-1, DCAL-2, C-type lectin domain family 12 member A, CD371, Mouse, Flow Cytometry, Immunology, Antibodies

Product Reviews

  Title Rating Date
- There are currently no reviews for this product. Be the first to review this product to qualify for a $100 Amazon gift card drawing. -
See more reviews using the Reviews Library

Product FAQs

There are no FAQs for this product. For a complete list of FAQs on all our products, visit our FAQ page.
Related Products

Purified Rat IgG2a, κ Isotype CtrlRTK2758FC, ICC, IF, IHC, IP, WB
Cell Staining BufferFC, ICC, ICFC
RBC Lysis Buffer (10X)FC, ICFC

Other Formats

APC anti-mouse CD371 (CLEC12A)5D3/CLEC12AFC
PE anti-mouse CD371 (CLEC12A)5D3/CLEC12AFC

Related Pathways


Related Categories

Immunology > Human Immunology > CD and Related Molecules > CD371 (CLEC12A) > 5D3/CLEC12A
Immunology > Mouse Immunology > Monocyte/Macrophage > CD371 (CLEC12A)
Immunology > Human Immunology > B Cells > CD371 (CLEC12A)
Immunology > Human Immunology > Innate Immunity > CD371 (CLEC12A)
Immunology > Human Immunology > Dendritic cells > CD371 (CLEC12A)
Immunology > Mouse Immunology > B Cells > CD371 (CLEC12A)
Immunology > Mouse Immunology > Dendritic cells > CD371 (CLEC12A)
Immunology > Human Immunology > Monocyte/Macrophage > CD371 (CLEC12A)

*These products may be covered by one or more Limited Use Label Licenses (see the BioLegend Catalog or our website, BioLegend products may not be transferred to third parties, resold, modified for resale, or used to manufacture commercial products, reverse engineer functionally similar materials, or to provide a service to third parties without written approval of BioLegend. By use of these products you accept the terms and conditions of all applicable Limited Use Label Licenses. Unless otherwise indicated, these products are for research use only and are not intended for human or animal diagnostic, therapeutic or commercial use.

Version: 3 Revision Date: 2015-01-22
Copyright © 2014 BioLegend, Inc. All rights reserved.